Enzymes — EdVibe Simulation

How to use: Blue substrate molecules bounce around the enzyme. When one fits into the enzyme's active site, the reaction happens and it's released as two yellow products. Try changing the temperature. Watch what happens past the optimum — the active site changes shape and substrates no longer fit. That's denaturation, and it's permanent.

Notice: rate is fastest at 37 °C (body temperature). Below that, particles move slower so there are fewer collisions. Above that, the enzyme's active site denatures — it changes shape permanently, so the substrate no longer fits. That's why high fever is dangerous. Same idea applies to pH.